Phytopharmaceutical Research Summary Sherman Zhao, MD, PhD ABSTRCT An integrative approach for treating cancer should target the multiple intracellular pathways that support tumour development and should minimize normal-tissue toxicity. Many traditional medicine manifests anticancer activities. The present article focuses on Dammarane Sapogenins, a group of compounds with anticancer activity generatedContinue Reading
Tsu-Tsair Chi, PhD ABSTRACT Angiogenesis inhibition has been a major breakthrough in cancer research and is undoubtedly one of the reasons for the decline in cancer incidence and mortality. In cases of estrogen-related cancers, the use of aromatase inhibitors has been quite successful in reducing recurrence and improving overall survivalContinue Reading
Dong Wang, Baochang Cai, Guangming Yang, Ying Gao, Hao Cai, Junsong Li, Xiao Liu ABSTRACT The medicinal plants of Oxytropis species, which contain greatly abundant active compounds and exert prominently effective biological activities, have been widely used in Tibetan and Mongolian medicine. The antitumor activities of Oxytropis have been extensivelyContinue Reading
Sherman Zhao, MD, PhD ABSTRACT Currently it does not exist a full understanding of the underlying mechanisms of cancer. Two potential models to explain the development, maintenance, and recurrence of cancer include the stochastic model and the stem cell model. Recent insights into the function and characteristics of cancer stemContinue Reading
Brian Leung, ND, DC Abstract Vitamin C was a discovery that led to the prevention of scurvy. In modern science, its close resemblance in structure to glucose has enabled it to be recognized by cancer cells and made it successful in treating several cancers via intravenous routes in pharmacological doses.Continue Reading
贺福长, 李德伦, 毛天球 摘要 采用噻唑兰 (MTT) 方法观察 0.25T 的恒定强磁场对 4 种口腔颌面部癌细胞体外培养的影响. 发现磁场对这 4 种癌细胞均有不同程度的抑制作用, 其中腺癌细胞比鳞癌细胞对磁场更为敏感, 并且随着磁场作用时间加长, 这种抑制作用更明显. 平阳霉素对体外培养的人粘液表皮样癌 MEC-1系细胞生长有较强的抑制作用, 而与 0.25T 恒定强磁场联合应用后, 抑制作用明显增强, 两者有相加用. 关键词: 磁场; 癌; 平阳霉素 我们观察了 0.25T 恒定强磁场以及其联合平阳霉素对人口腔颌面部 4 种癌细胞体外培养的影响, 报道如下. 材料和方法 癌细胞系采用第四军医大学口腔医学院中心实验室建立的传代细胞系即人粘液表皮样癌 MEC-1系, 腺样囊性癌 SACC-83 系, 舌癌 Tca8113 系, 牙齦癌 Ca9-22 系; 平阳霉素为天津市河北制药总厂出品; 磁场由 N, SContinue Reading
第四军医大学口腔医学院领面外科 – 贺福长, 毛天球, 李德伦, 吴军正, 贾宝军 西北上业大学 – 邹光荣, 唐卫, 姜战军 〔摘要〕 利用稀土永磁体磁片形成 0.25T 的恒定强磁场, 观察该强度磁场对四种口腔颌面部癌细胞体外培养的影响, 发现对这四种癌细胞均有不同程度抑制作用, 其中两种腺癌细胞比两种鳞癌细胞对磁场更敏感些, 并发现随着磁场作用时间加长, 这种抑制作用更明显. 磁性脂质体被体外培养的癌细胞摄取后将会增强这种抑制作用. 关键词: 磁生物效应; 脂质体; 恒定强磁场; 癌 近年来, 生物磁学的基础研究和应用研究发展迅速, 其中磁场对细胞尤其是肿瘤细胞的生物效应研究尤引人注目, 但目前为止对人的肿瘤细胞研究很少, 对人口腔颌面部恶性肿瘤细胞的研究目前尚未见有报道. 本文拟通过对 0.25T 恒定强磁场对人口腔颌面部四种癌细胞体外培养的影响观察, 希望对恶性肿瘤磁疗学提供有益的参考资料. 1 材料与方法 1.1 癌细胞系采用本院中心实验室建立的传代细胞系即人粘液表皮样癌 MEC-1 系, 腺样囊性癌 SACC-83 系, 舌癌 Tca8113 系及牙齦癌 Ca9-22 系.Continue Reading